Diabetes medications, including insulin – variable effects reported, always consult a doctor before use if you have diabetes. Other possible, but unsubstantiated, interactions include: Iron supplements – several informative sites state Garcinia cambogia contains iron; however, most supplements use an extract of Garcinia cambogia, which is unlikely to contain high amounts of iron. Several other fruits also contain iron but are not reported as interacting with iron supplements
Serotonin-stimulating antidepressants or pain medications – one mouse study suggested Garcinia cambogia had a serotonin-enhancing effect; however, this has not been verified in humans
Asthma medications (including Montelukast) – one documented case study of a woman who developed fatal liver failure after taking two dietary supplements for two weeks on top of her usual asthma medications, including Montelukast
Statins – this is based on the fact that statins can cause rhabdomyolysis (a destruction of muscle cells). One case study reported rhabdomyolysis in a women taking a combination weight loss supplement (of which one of the ingredients was garcinia cambogia); so some experts are concerned about a theoretical additive effect with statins.
Warfarin – A man taking warfarin together with a combination herbal product that included Garcinia cambogia, reported a change in his INR (a measure of the clotting ability of the blood) that returned to normal after discontinuation of the supplement.
In addition, supplements of Garcinia cambogia may contain other nutrients such as calcium and potassium which may cause additive effects in people already supplementing their diet with these nutrients. Always read the label to see what ingredients are actually contained in your supplement, and always seek your doctor’s advice before taking any dietary supplements particularly if you take other medications.
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